If needed, daily dosing is extended for another eight weeks.  
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An individual with Pick disease should not smoke, both for health and safety reasons.  
Actigraphy is another technique to assess sleep-wake patterns over time.  
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Supplementation with calcium carbonate is reported to lead to reduced risk of adenomas (nonmalignant tumors) in the colon, a precursor to colon cancer, but it is not known if this will ultimately translate into reduced cancer risk.  
How mast cell inhibitors work: These drugs prevent the release of histamine and other chemicals that cause allergic symptoms from mast cells when an individual comes into contact with an allergen like pollen.