Another interesting feature of further development of the primitive gut is its cranial-to-caudal progression.  
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IN THIS ARTICLEHeartburn FAQs IntroductionWhy does the acid back up into the esophagus?Do spicy foods cause heartburn?Why do I always get heartburn at night?Sometimes I get a sour taste in my mouth when I bend over--what is that?How common is heartburn?Is heartburn a serious condition?What kinds of complications are caused by frequent heartburn?If I have heartburn, should I see my health care provider?Aren't there any tests for heartburn?What is the treatment for heartburn?What are my options if these treatments don't work?When is surgery needed for heartburn?How can I prevent heartburn?What happens if I stop treatment?For More InformationWeb LinksMultimediaSynonyms and KeywordsAuthors and EditorsHow common is heartburn?About 30% of adults experience occasional heartburn, while 10% experience heartburn every day.  
This is often seen in people with poor immune systems, certain types of meningitis, and severe abdominal pain.  
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The incidence of cough is shown below.  
Cigarette smoking is the most common cause of COPD.